Thanks for the advice...

But deleting the files and running scans (Microsoft Antispyware, Adaware and Norton) haven't fixed it. Each time I reboot my computer there are hundreds of new files in c:/uploads! And I get the same trojans, etc, showing up in my scans.

It's driving me mad as my computer is now soooo slow and I can't concentrate on my work. Does anyone have any other advice?

I also tried System Restore, going back several weeks several times, but each time it failed. Grrrr!

Any other advice is much appreciated!

cheers