Right-clicking the Limewire actual program and going to properties and change compatability setting & choose either win 2000 or NT. BTW try both to see if either will work.

BTW I'm wondering if it might be an idea to reinstall LW. But get the "Offline" installer, not the online recommended one.
Another option is to uninstall it by using the Start menu > Programs > LW > Uninstall. Then get this version Download ‘Other’ version & simply unzip & use!