Mouse Control Issue
 

My problem happens after Limewire loads, the screen to Upgrade to LimePro comes up and either here, or after I get that screen closed, the mouse doesn't seem to register. I can't switch from the general search screen to specific media types, I can't click on downloaded files. I sometimes can work through keyboard shortcuts, but not much else.

I hope this is clear enough, and if anyone has any ideas for help, I'd appreciate it!

It could be a Java issue...
Try uninstalling your Java from the add/remove programs and then re-install the JRE 5.11 offline version....
Archive: Download Java 2 Platform Standard Edition (J2SE) 5.0 Update 11

If that does not help with your problem try deleting your preference folder...
Fixes for Limewire when LW isn't operating as it should