If you mean Play_mp3.exe then no, it's not safe. It's malware.

Check out the links below for more info. If you Google play_mp3.exe you'll find even more info
http://en.wikipedia.org/wiki/Play_mp3.exe_(trojan)

PLAY_MP3.exe – Media File Trojan! Bill Mullins’ Weblog – Tech Thoughts

play_mp3.exe - What is play_mp3.exe?

PLAY_MP3[1]..EXE, Prevx

If you've downloaded & run play_mp3.exe then you need to update your AV program & scan your computer.
If you don't have an AV program installed, see post #2 of this thread for some good free ones. I'd also scan with Malwarebytes (see link in post #2) - make sure to update the program before you scan. See how you go after that. If in doubt, you could scan with other antispy/adware programs as shown in post #2 or in the link below

More links here to online scans & antispy/adware programs etc: http://www.gnutellaforums.com/open-d...uld-aware.html