I tried a lot of things regards mc afee, vista and LW. The only solution to keep you antivirus and run Lime wire without problems is:

1.- go to control panel
2.- uninstall programs
3.- select mc afee
4.- unistall privacy service and spam killer
5.- restart you computer and you'll be able to conect to internet and use Lime Wire at the same time as well as you internet explorer.

I had to call mc afee to figure this out cuz was been a pain in the a.... this problem and this is the only solution that they have for now until they fix those compatibility problems with vista, mc afee and LW.

I have my laptop with vista, lime wire and explorer working really good, any question contact me @* email address removed*

Hope this work for you folks!!!