This is my problem.....
Q: When I try to run the Windows installer I get an error
message during setup initialization Error 1608: Unable to
create InstallDriver instance.
This did not work --
A: This error indicates that InstallShield was unable to
successfully install one of its key components using
the “ISScript.msi” file. You can solve this problem by
downloading the file from here and double clicking on it. Once
you have done this, try running the LimeWire installer again.

I tried this...

If this does not work, there could also be a problem with
your “DCOM” permissions.
To set your DCOM permissions to the necessary values,
follow these steps:

Launch Dcomcnfg.exe from the Start, Run option.
Go to the Default Security tab, Default Access
Permissions section and click Edit Default.

Could not do this --

Now set the privilege "Allow Access" for yourself from the
drop down list.
Click ok and close Dcomcnfg.exe
Run the setup again.

HELP!!!