It's McAfee that is more than likely your main concern....
There have been two solutions posted here on getting McAfee and limewire to work together...Have a look at them try them and see how you go...
http://www.gnutellaforums.com/genera...-solution.html http://www.gnutellaforums.com/258193-post45.html
As I said before McAfee would be one of your main concerns, if you still cant get a connection after attempting those could you post your details so I can see if there is anything else that may be blocking you...
http://www.gnutellaforums.com/connec...-you-post.html