You just delete that LW preferences folder. When you next open LW, it will ask you the set up options again. That's why it's wise to make a note of your settings before you delete the folder. Things like speed settings, any keywords filtered, any ip's banned, changing days to keep incompletes to a large number like 999.
You will find instructions about how to delete the prefs folder for Vista in the Vista section of the forums (check the sticky at top of that section.)
Normally you should only have one software firewall operational. If you choose to use Norton, then disable the Windows firewall. They DO clash & cause problems. With Norton you need to be careful with the firewall. Everytime you update Norton or LimeWire, you need to reset your clearance for LW in the firewall.
Reconfiguring Norton Firewall
What model linksys router do you have?