First thing to try: Delete LW's preferences folder when LW's properly closed. See point 3 here & also point 2 if you've used older versions of LW in the past (there could be a folder in either location).
Fixes for LimeWire
This will kill all of your settings within options, you'll have to go back through afterwards & reset things. If you're not sure of your settings, go through LW's tools > options & write them all down, so that you can reset things later.
Do you also have the Sygate firewall? If so, make sure that the Windows firewall is off & configure Sygate to allow LW.
http://www.gnutellaforums.com/connec...-firewall.html
If you're still stuck, please give us your details.
System details - help us to help you (click here)