Try these things:
1. Make a note of all your settings, then ry deleting your LW Preferences folder whilst LW is closed; instructions here: Point #2 & 3 in Fixes for Limewire (sample image included at bottom of page.)

2. Go to Tools > Options > Advanced > Performance & disable all options on that page. Press apply button.

3. Do as mickjapa108 suggested. Also, after opening LW, let it settle for a few mins before using. And don't use the resume/find sources function on all your files. If you use it, use it on only 1-3 files at a time.

4. If still problems, Tip: Purge the Downloads Queue! (click on blue link)