Are you using Pest Patrol? Check out the thread below
http://www.gnutellaforums.com/open-d...-limewire.html

If that's not the problem, open task manager (ctrl/alt/del) & see if there's a LW process running. If there is, end the process. Now reinstall LW & make sure to use the offline installer (when you click to download LW & the dialog box pops up, cancel that...now use the option to download the offline installer). There's no need to uninstall your current LW, when you install a new version it'll automatically remove the old one