I have searched the forums for this topic but can't figure out what pertains to my PC and what doesn't.

I recently re-installed Windows XP Home, have SP2 and all the latest updates. Tried to install Limewire again today and the setup wizard is blank, I can find the cancel button but not anything else.

Does anyone know why this is happening?

Thanks.

It Might be a Java issue.

First of all, install Java. Download the JRE offline installer & remove any other Java versions installed (via Add/Remove Programs) before you install the latest Java.
Java SE Downloads

After Java's installed, install LW. When you click to download the LW installer, cancel the dialog box which pops up...now use the option to download the offline installer.
Lime Wire » Download LimeWire

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That worked great, thank you!