Reinstall both LW & Java; Reinstallation Technique
For Vista, you should right-click installer & choose run as Administrator. If still issues try the other fixes point 3 & 5 in Fixes for LW link.

To Lord-of-the-RIngs.....Thank you for your gudance in helping me load LW. Your solution was spot-on!
Thanks Again.
bwatkins

i done everything you say to do here and still cant load limewire 5.5. just comes up cant load limewire, need to install again. when i go to users app data roaming, but there is no limewire folder to delete perferences.
do you konw what could be wrong with my computer. it a pretty new computer. with windows 7.