If ELoXL suggestions don't work then it is probably a virus. See these two threads:

LimeWire continually Popping up every few seconds & also Opening at System Startup,

WARNING: Viruses on network you should be aware of!

If you have trouble getting rid of it go to NorbiesWorld (click on link) >> Viruses, Trojans, Spyware etc & All Other Computer Help!

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If it ain't broke, fix it till it is!