I haven't tried Wine though I downloaded it at a friend's pushy recommendation. lol
No windows window interface, simply run the apps as though you were running them in windows but on either Linux or OSX.

I'm just so used to using several virtual windows interfaces (parallels), win 2000 through to win 7 to simulate what each has so I can test things out. Each saved to a disk image, and each with history options in case something goes wrong.
But Wine sounds like a breeze running win apps as though they were native to your system.