I'm no computer expert by any stretch, but I do know a thing or two. I've always thought the scenario went something like this...

1) I search for "sndjfrti"
2) Main superspam computer picks up the search term via search monitoring
3) Main superspam computer sends command to 40 other minorspam computers to make a copy of "StupidIPodPic.jpg" and rename it "s_n_d_j_f_r_t_i.jpg"
4) 40 hosts suddenly show up in my search results for the file "s_n_d_j_f_r_t_i.jpg"

Based on your Resident Evil story, I wonder if it's more along the lines of...

1) I search for "sndjfrti"
2) Computer of hacker working for IPodSpamCo picks up the search term via search monitoring
3) Hacker computer orders 40 computers with trojan viruses to rename "HiddenIPodPic.jpg" as "sndjfrti.jpg"
4) 40 hosts suddenly show up in my search results for the file "sndjfrti.jpg"

I've always tended to believe that my first theory is correct, because you can never browse the hosts of these goofball files. When I identify these files, I typically right click, verify that I can not browse host, and block host.

What would be real nice would be if the wonderful people that maintain Limewire would allow us to block ALL of the hosts in one shot.