hmm ... I still get the impression that it's a playlist issue. I know winamp also uses or can use playlists. Have you tried removing the listing from winamp of the song, then re-adding from the new location?

Also, does the new location have same user permissions to the one you were using on F drive? Check user permissions in both locations.
eg: one location might be set to your user account permissions, and the new location to another user who might be admin account only permissions. This can be changed via the control panels.

I don't create playlists. I simply click on the song and it plays, Winamp is my default player. I am the only user of this PC, I have Admin privileges. I did not have this problem at all until I updated/upgraded to LW ver 4.16.6. I initially started with 4.14.1 and had no problem Moving files from any folder to any other folder and they'd play. I'm Copying or Moving from Folders on the same drive, as a general rule, until I need to sort them into alphabetical folders. Then I'll move them to another drive.

This lockout after moving has only begun with the last two upgrades. I have D/L'd LimeWireWin 4.16.7.1 but haven't installed it yet. Could be that will fix it. I used Control Panel A & D prgms to remove previous versions. When I D/L a file, I usually SAVE IT, then Run it from the saved location. Unfortunately, I've deleted the earlier versions of the previous editions of LW.

Thanks for your assistance.
Juan